{"id":11475,"date":"2012-06-20T18:52:52","date_gmt":"2012-06-20T21:52:52","guid":{"rendered":"http:\/\/revistapesquisa.fapesp.br\/?p=11475"},"modified":"2012-06-20T18:52:52","modified_gmt":"2012-06-20T21:52:52","slug":"heart-problems-scent","status":"publish","type":"post","link":"https:\/\/revistapesquisa.fapesp.br\/en\/heart-problems-scent\/","title":{"rendered":"Heart problems&#8217; scent"},"content":{"rendered":"<p>A non-invasive biomarker can diagnose, in seven minutes, the severity of heart failure, by evaluating the acetone exhaled by the patient. The project, which had FAPESP support, began as the result of an observation made by physician Fernando Bacal from InCor, the Heart Institute of the University of S\u00e3o Paulo (USP). He noticed that patients with severe heart failure released an odd smell when their condition was not under control. After this, together with USP\u2019s Chemical Institute, he developed a portable device to capture the exhaled substance. \u201cThe air collected was analyzed in a mass spectrometer and the compound that was identified was acetone,\u201d says Bacal. Comparative tests were then conducted with another substance, called BNT, having been taken from patients\u2019 blood. This is the gold standard of heart failure markers. Both the biomarker and the portable collecting device have been patented.<\/p>\n","protected":false},"excerpt":{"rendered":"Biomarker allows diagnosis based on acetone released by patient","protected":false},"author":6,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[168],"tags":[247],"coauthors":[785],"class_list":["post-11475","post","type-post","status-publish","format-standard","hentry","category-technoscience","tag-medicine"],"acf":[],"_links":{"self":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/11475","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/comments?post=11475"}],"version-history":[{"count":0,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/11475\/revisions"}],"wp:attachment":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/media?parent=11475"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/categories?post=11475"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/tags?post=11475"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/coauthors?post=11475"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}