{"id":144099,"date":"2014-02-07T15:22:26","date_gmt":"2014-02-07T17:22:26","guid":{"rendered":"http:\/\/revistapesquisa.fapesp.br\/?p=144099"},"modified":"2014-02-07T15:22:26","modified_gmt":"2014-02-07T17:22:26","slug":"dopamine-immediacy","status":"publish","type":"post","link":"https:\/\/revistapesquisa.fapesp.br\/en\/dopamine-immediacy\/","title":{"rendered":"Dopamine and immediacy"},"content":{"rendered":"

\"\"Daniel Bueno<\/span>A timely variation in a gene that helps regulate the amount of dopamine in the brain seems to influence a specific aspect of impulsivity related to decision-making.\u00a0 This gene stores the recipe of the enzyme that degrades dopamine and is found in two versions:\u00a0 one generates a more active enzyme and the other a less effective enzyme.\u00a0 By analyzing the performance of healthy individuals on two neuropsychological tests, researchers at the Federal University of Minas Gerais (UFMG) verified that those who have two copies of the allele that manufactures the less active enzyme performed worse on a task that evaluates the long-term consequences of decision-making \u2013 what is known as decision-making impulsivity.\u00a0 On one of the tests, Leandro Malloy-Diniz subjected 192 study participants to a virtual game in which they won or lost money by choosing playing cards from four different piles.\u00a0 Before beginning the game, the researcher told them that some of the piles were more profitable than others.\u00a0 The cards in certain piles yielded bigger profits, but they also generated bigger losses, while those from the other piles generated more modest winnings and fewer losses.\u00a0 The people who produced the less efficient enzyme \u2013 and had higher levels of dopamine \u2013 performed worse on this task, but not on another that measured the capacity to pay attention during an activity and the ability to inhibit a particular motor response (PLoS One<\/i>, September 10, 2013).\u00a0 \u201cThese results reinforce the hypothesis that different aspects of impulsivity are independent and derived from different neurobiological bases,\u201d the researchers write.<\/p>\n","protected":false},"excerpt":{"rendered":"Dopamine gene variation seems to influence impulsivity","protected":false},"author":475,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[168],"tags":[247],"coauthors":[785],"class_list":["post-144099","post","type-post","status-publish","format-standard","hentry","category-technoscience","tag-medicine"],"acf":[],"_links":{"self":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/144099","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/users\/475"}],"replies":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/comments?post=144099"}],"version-history":[{"count":0,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/144099\/revisions"}],"wp:attachment":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/media?parent=144099"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/categories?post=144099"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/tags?post=144099"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/coauthors?post=144099"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}