{"id":145747,"date":"2009-03-14T17:41:37","date_gmt":"2009-03-14T20:41:37","guid":{"rendered":"http:\/\/revistapesquisa.fapesp.br\/?p=145747"},"modified":"2014-03-14T17:44:32","modified_gmt":"2014-03-14T20:44:32","slug":"active-kidneys","status":"publish","type":"post","link":"https:\/\/revistapesquisa.fapesp.br\/en\/active-kidneys\/","title":{"rendered":"Active kidneys again"},"content":{"rendered":"<p>Stem cells extracted from bone marrow helped rats&#8217;\u00a0 kidneys function again.\u00a0 The rats had a condition similar to human chronic renal disease, which is the progressive loss of the kidneys&#8217; capacity to filter blood, a condition that afflicts approximately 70 thousand people in Brazil.\u00a0 An experiment coordinated by nephrologist L\u00facia Andrade, from the University of S\u00e3o Paulo&#8217;s Medical School, involved the application of two treatment strategies to the rodents with 20% of their renal functions \u2013 one kidney and two-thirds of the other kidney had been surgically extracted to simulate the problem.\u00a0 Two weeks after surgery, a group of rats received 2 million stem cells injected into their blood.\u00a0 Another group received three such injections.\u00a0 In the fourth month after treatment, the first and second groups had recovered 50% of their blood filtering capacity, according to an on-line article written by the group, together with a group of researchers from the Federal University of S\u00e3o Paulo.\u00a0 The article was published in the December issue of <i>Stem Cells<\/i>.\u00a0 \u201cIn human beings, 20% of the renal capacity entails the need for hemodialysis,\u201d explains L\u00facia. With 50% renal capacity, it is possible for patients to lead a normal life, provided they have medical follow-up.<\/p>\n","protected":false},"excerpt":{"rendered":"Stem cells from bone marrow helps kidneys to function again","protected":false},"author":475,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[168],"tags":[210,247],"coauthors":[785],"class_list":["post-145747","post","type-post","status-publish","format-standard","hentry","category-technoscience","tag-cellular-biology","tag-medicine"],"acf":[],"_links":{"self":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/145747","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/users\/475"}],"replies":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/comments?post=145747"}],"version-history":[{"count":0,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/145747\/revisions"}],"wp:attachment":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/media?parent=145747"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/categories?post=145747"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/tags?post=145747"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/coauthors?post=145747"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}