{"id":177756,"date":"2015-03-24T17:13:18","date_gmt":"2015-03-24T20:13:18","guid":{"rendered":"http:\/\/revistapesquisa.fapesp.br\/?p=177756"},"modified":"2015-04-24T17:17:25","modified_gmt":"2015-04-24T20:17:25","slug":"a-vaccine-for-chagas-disease","status":"publish","type":"post","link":"https:\/\/revistapesquisa.fapesp.br\/en\/a-vaccine-for-chagas-disease\/","title":{"rendered":"A vaccine for Chagas disease"},"content":{"rendered":"<p>A compound developed in Brazil may be used in the future as a therapeutic vaccine against Chagas disease. The compound successfully protected 80% of mice that had been exposed to the parasite that causes the illness. The treated animals exhibited the same longevity as disease-free animals (<em>PLOS Pathogens<\/em>, January 24, 2015). Conversely, every one of the rodents included in a third group \u2013 infected, but left untreated \u2013 had died by the end of the 250-day experiment. The vaccine also reduced the parasite burden of infected mice to one-fifth of the amount found in untreated animals, in addition to decreasing the incidence of cardiac arrhythmia to 33%. Usually, all infected animals present the problem. Coordinated by Maur\u00edcio Martins Rodrigues at the Federal University of S\u00e3o Paulo (Unifesp), the researchers who participated in the study include a research group at the National Institute for Vaccine Science and Technology (INCTV), whose members include biophysicist Joseli Lannes-Vieira, principal author of the paper published in <em>PLOS<\/em>.<\/p>\n","protected":false},"excerpt":{"rendered":"Compound developed in Brazil may be a vaccine candidate","protected":false},"author":475,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[168],"tags":[247,260],"coauthors":[785],"class_list":["post-177756","post","type-post","status-publish","format-standard","hentry","category-technoscience","tag-medicine","tag-public-health"],"acf":[],"_links":{"self":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/177756","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/users\/475"}],"replies":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/comments?post=177756"}],"version-history":[{"count":0,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/177756\/revisions"}],"wp:attachment":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/media?parent=177756"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/categories?post=177756"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/tags?post=177756"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/coauthors?post=177756"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}