{"id":18492,"date":"2001-05-18T08:30:23","date_gmt":"2001-05-18T11:30:23","guid":{"rendered":"http:\/\/revistapesquisaclone.fapesp.br\/2006\/08\/17\/investigation-network\/"},"modified":"2016-02-11T15:39:44","modified_gmt":"2016-02-11T17:39:44","slug":"investigation-network","status":"publish","type":"post","link":"https:\/\/revistapesquisa.fapesp.br\/en\/investigation-network\/","title":{"rendered":"Investigation network"},"content":{"rendered":"

\"\"NEW HAMPSHIRE University<\/span>The Viral Genetic Diversity Network (VGDN) is set up and working. Its initial configuration will include 18 laboratories, 10 located in the metropolitan region of S\u00e3o Paulo and 8 in towns in the country. These laboratories were selected from the 35 proposals presented to FAPESP that will finance the project that began last December with the edictal inviting interested institutions to participate in the initiative. “We were able to attract to the network research centers from the main regions of the state. Perhaps the only important region that was stayed out was Santos”, says Eduardo Massad, of the School of Medicine of USP, one of the coordinators of the VGDN.<\/p>\n

The laboratories are going to take up the task of sequencing the DNA of samples of the four viruses present in the state: HIV-1, the main cause of Aids; HCV, the transmitting agent for hepatitis C; Hantavirus, responsible for a mysterious and rare syndrome of the lungs; and the respiratory syncytial virus VRS, which provokes infections in the respiratory tract, mainly in children. The investment in the setting up the network is US$ 8 million, to be spent over a three- year period.<\/p>\n

A policy of prevention
\n<\/strong>What is the significance of this work? Without the mapping of the genetic code of a significant quantity of the viruses that circulate and infect the population of a determined location, it is impossible to establish the dominant variations of the pathological agents in this location. To understand the most common types of the viruses present in the state will allow the planning of a better epidemiological policy of prevention and treatment of illnesses, as well as the generation of important knowledge for scientific research. Enabling the laboratories of various towns of S\u00e3o Paulo to cope with the viruses, the VGDN is also following the objective of providing the state with a group of laboratories which, in the future, may be used permanently and ordinarily by the Health Department of the State.<\/p>\n

Three levels
\n<\/strong>According to the degree of competence and the conditions of security in the handling of the virus demonstrated at the time of registration, the 18 laboratories were divided into three levels. At level 1, L1, the most basic, 12 institutions were selected, which initially are suitable for work only with the viruses HIV-1 and HCV. At level 2, L2, five laboratories were grouped together. And these are able to deal with these two pathological agents as well as the VRS.<\/p>\n

Only one center reached the most advanced stage of the project, level 3, L3, being therefore, capable of carrying out laboratory analysis with all four viruses. “As we expected, the network is beginning with a heterogeneous grouping. Our goal is to go on, step by step, improving the performance of the units that are at the bottom of the VGDN. In 2002, we would like all of the laboratories to have reached level 2”, says Dr. Eduardo Massad.<\/p>\n

THE LABORATORIES OF THE VGDN<\/strong><\/p>\n

Level L1<\/strong>
\nAlberto Jos\u00e9 da Silva Duarte – Medical School of USP
\nDavid Jamal Hadad – State Health Department
\n\u00c9dimo Garcia de Lima – Medical School of S\u00e3o Jos\u00e9 do Rio Preto
\nF\u00e1bio Caldas de Mesquita – Municipal Health Department of S\u00e3o Paulo
\nFernando Lopes Gon\u00e7ales Junior – School of Medical Sciences of Unicamp
\nFlair Jos\u00e9 Carrilho – Medical School of USP
\nJos\u00e9 Fernando Garcia – Veterinary Medicine of Unesp\/Ara\u00e7atuba
\nJos\u00e9 Luiz Caldas Wolff – University of Mogi das Cruzes
\nLeonardo Jos\u00e9 Richtzenhain – School of Veterinary Medicine and Zoo Technology of USP
\nMaria Ines de Moura Campos Pardini -Medical Faculty of Unesp\/Botucatu
\nOsvaldo Augusto Brazil Esteves Sant’AnnaButantan Institute
\nSang Won Han – Unifesp<\/p>\n

Level L 2<\/strong>
\nCl\u00e1udio S\u00e9rgio Pannuti – Medical School of USP
\nEurico de Arruda Neto – Medical School of Ribeir\u00e3o Preto of USP
\nJo\u00e3o Manuel Grisi Candeias – Institute of Biosciences of Unesp\/Botucatu
\nMirthes Ueda – Adolfo Lutz Institute
\nPaula Rahal\/Eloiza Helena Tajara da Silva – Institute of Biosciences, Letters, and Exact Sciences of Unesp\/S\u00e3o Jos\u00e9 do Rio Preto<\/p>\n

Level L3<\/strong>
\nBenedito Ant\u00f4nio Lopes da Fonseca\/Luiz Tadeu Moraes Figueiredo – Medical School of Ribeir\u00e3o Preto of USP<\/p>\n","protected":false},"excerpt":{"rendered":"Selected laboratories will receive US$ 8 million to sequence four viruses","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[166],"tags":[],"coauthors":[93],"class_list":["post-18492","post","type-post","status-publish","format-standard","hentry","category-policies-st-en"],"acf":[],"_links":{"self":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/18492","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/comments?post=18492"}],"version-history":[{"count":0,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/18492\/revisions"}],"wp:attachment":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/media?parent=18492"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/categories?post=18492"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/tags?post=18492"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/coauthors?post=18492"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}