{"id":225384,"date":"2016-10-04T12:24:02","date_gmt":"2016-10-04T15:24:02","guid":{"rendered":"http:\/\/revistapesquisa.fapesp.br\/en\/?p=225384"},"modified":"2016-10-04T12:24:02","modified_gmt":"2016-10-04T15:24:02","slug":"only-diseased-cells","status":"publish","type":"post","link":"https:\/\/revistapesquisa.fapesp.br\/en\/only-diseased-cells\/","title":{"rendered":"Only diseased cells"},"content":{"rendered":"<div id=\"attachment_225385\" style=\"max-width: 300px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-225385\" src=\"http:\/\/revistapesquisa.fapesp.br\/wp-content\/uploads\/2016\/09\/Tecno_RevistaFapesp.jpg\" alt=\"Graphic representation of nanoparticles interacting with a tumor cell\" width=\"290\" height=\"211\" srcset=\"https:\/\/revistapesquisa.fapesp.br\/wp-content\/uploads\/2016\/09\/Tecno_RevistaFapesp.jpg 290w, https:\/\/revistapesquisa.fapesp.br\/wp-content\/uploads\/2016\/09\/Tecno_RevistaFapesp-120x87.jpg 120w, https:\/\/revistapesquisa.fapesp.br\/wp-content\/uploads\/2016\/09\/Tecno_RevistaFapesp-250x182.jpg 250w\" sizes=\"auto, (max-width: 290px) 100vw, 290px\" \/><p class=\"wp-caption-text\"><span class=\"media-credits-inline\">Mateus Cardoso\/LNLS<\/span>Graphic representation of nanoparticles interacting with a tumor cell<span class=\"media-credits\">Mateus Cardoso\/LNLS<\/span><\/p><\/div>\n<p>Transporting an antitumor compound through the bloodstream and having it target only diseased cells without damaging healthy ones is a strategy currently being studied in many laboratories around the world. In Brazil, an experiment headed by Mateus Borba Cardoso of the National Synchrotron Light Laboratory (LNLS) used folate, a type of vitamin B, to envelop silica nanoparticles and increase their ability to interact with tumor cells. The nanoparticles contained a compound to destroy cancer cells. \u201cTumors are excellent folate receptors,\u201d says Cardoso. The nanoparticles were filled with curcumin, a substance extracted from turmeric (<em>Curcuma longa<\/em>) that has been studied as an anticancer agent (<a href=\"http:\/\/revistapesquisa.fapesp.br\/en\/2010\/02\/01\/poison-in-the-medicine\/?cat=ciencia\" target=\"_blank\">see <em>Pesquisa FAPESP <\/em>Issue n\u00ba 168<\/a>). In the experiment, conducted in collaboration with the Biosciences National Laboratory (LNBio)\u00a0and the National Nanotechnology Laboratory (LNNano) and funded by FAPESP, the tumor cells were destroyed and the healthy cells were scarcely affected (<em>Langmuir<\/em>, April 5, 2016).<\/p>\n","protected":false},"excerpt":{"rendered":"Nanoparticles increase the ability to interact with tumor cells","protected":false},"author":475,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[168],"tags":[],"coauthors":[785],"class_list":["post-225384","post","type-post","status-publish","format-standard","hentry","category-technoscience"],"acf":[],"_links":{"self":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/225384","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/users\/475"}],"replies":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/comments?post=225384"}],"version-history":[{"count":0,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/225384\/revisions"}],"wp:attachment":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/media?parent=225384"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/categories?post=225384"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/tags?post=225384"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/coauthors?post=225384"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}