{"id":235214,"date":"2017-03-27T15:32:36","date_gmt":"2017-03-27T18:32:36","guid":{"rendered":"http:\/\/revistapesquisa.fapesp.br\/en\/?p=235214"},"modified":"2017-03-27T15:32:36","modified_gmt":"2017-03-27T18:32:36","slug":"new-job-for-an-old-drug","status":"publish","type":"post","link":"https:\/\/revistapesquisa.fapesp.br\/en\/new-job-for-an-old-drug\/","title":{"rendered":"New job for an old drug"},"content":{"rendered":"<p>Chlorpromazine, an anti-psychotic medication used to treat schizophrenia, is being tested against leukemia, a type of cancer that begins in the bone marrow and attacks white blood cells. Researchers at the Center for Natural and Human Sciences, of the Federal University of the ABC (UFABC), in Santo Andr\u00e9, used a polymer to encapsulate chlorpromazine and thus create a nanostructured system that makes it easier for the drug to enter cells. The system proved effective in fighting leukemia cells in vitro (<em>Pharmacological Research<\/em>, September 2016). \u201cThe effect on the tumor cells was greater when the drug worked in conjunction with the nanostructure rather than alone,\u201d says pharmacist Tiago Rodrigues, professor at UFABC and study coordinator, together with Professor Daniele Ribeiro de Ara\u00fajo. Researchers at the university are currently doing animal testing and studying the mechanism of the drug, in partnership with the Federal University of S\u00e3o Paulo (Unifesp).<\/p>\n","protected":false},"excerpt":{"rendered":"Medication used to treat schizophrenia is being tested against leukemia","protected":false},"author":475,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[168],"tags":[247,232],"coauthors":[785],"class_list":["post-235214","post","type-post","status-publish","format-standard","hentry","category-technoscience","tag-medicine","tag-pharmacology"],"acf":[],"_links":{"self":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/235214","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/users\/475"}],"replies":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/comments?post=235214"}],"version-history":[{"count":0,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/235214\/revisions"}],"wp:attachment":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/media?parent=235214"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/categories?post=235214"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/tags?post=235214"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/coauthors?post=235214"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}