{"id":249857,"date":"2017-12-05T17:46:56","date_gmt":"2017-12-05T19:46:56","guid":{"rendered":"http:\/\/revistapesquisa.fapesp.br\/?p=249857\/"},"modified":"2017-12-05T17:46:56","modified_gmt":"2017-12-05T19:46:56","slug":"zika-virus-vaccine-will-be-tested-in-brazil","status":"publish","type":"post","link":"https:\/\/revistapesquisa.fapesp.br\/en\/zika-virus-vaccine-will-be-tested-in-brazil\/","title":{"rendered":"Zika virus vaccine will be tested in Brazil"},"content":{"rendered":"<div id=\"attachment_249858\" style=\"max-width: 310px\" class=\"wp-caption alignright\"><a href=\"http:\/\/revistapesquisa.fapesp.br\/wp-content\/uploads\/2017\/12\/012-notas_255_02.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-249858\" src=\"http:\/\/revistapesquisa.fapesp.br\/wp-content\/uploads\/2017\/12\/012-notas_255_02-300x200.jpg\" alt=\"\" width=\"300\" height=\"200\" \/><p class=\"wp-caption-text\"><span class=\"media-credits-inline\">Joseph Xu \/ Michigan Engineering<\/span><\/a> Vials from the Leidos production line that will be used in the zika vaccine<span class=\"media-credits\">Joseph Xu \/ Michigan Engineering<\/span><\/p><\/div>\n<p>Through an agreement made in early 2017 with the National Institute of Allergy and Infectious Diseases (NIAID) in the United States, Brazil will take part in efficacy evaluation tests (phase 2) for a zika virus vaccine. Developed by the NIAID teams and identified as code VRC-ZKADNA085-00-VP, the vaccine proved to be safe and capable of activating the production of antibodies to fight the virus in animal models and initial testing (phase 1) in healthy individuals who were not infected. Physicians Jorge Kalil and Esper Kallas, professors at the University of S\u00e3o Paulo School of Medicine (FMUSP), will coordinate the tests in Brazil. \u201cWe started talking about having Brazil participate a year ago, when Barney Graham from NIAID, the inventor of the vaccine, was in Brazil,\u201d Kalil says. \u201cIt is a relatively promising and safe vaccine that can be produced quickly.\u201d He notes that the testing plan is being analyzed by the FMUSP Ethics and Research Commission; if approved, it will move on to the National Commission for Ethics in Research (CONEP) and to the Brazilian Health Surveillance Agency (ANVISA). Kalil hopes to begin testing in the second half of 2017 with a group expected to consist of 120 individuals. The Brazilian team plans to perform the phase 1 tests once again to check the safety of the vaccine in individuals who have already contracted dengue and take part in the phase 2 evaluations along with teams from the United States, Puerto Rico, Peru, Costa Rica, Panama and Mexico.<\/p>\n","protected":false},"excerpt":{"rendered":"Zika virus vaccine will be tested in Brazil","protected":false},"author":475,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[1651],"tags":[242,260],"coauthors":[785],"class_list":["post-249857","post","type-post","status-publish","format-standard","hentry","category-notes","tag-immunology","tag-public-health"],"acf":[],"_links":{"self":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/249857","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/users\/475"}],"replies":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/comments?post=249857"}],"version-history":[{"count":0,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/249857\/revisions"}],"wp:attachment":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/media?parent=249857"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/categories?post=249857"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/tags?post=249857"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/coauthors?post=249857"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}