{"id":397763,"date":"2021-07-19T14:59:51","date_gmt":"2021-07-19T17:59:51","guid":{"rendered":"https:\/\/revistapesquisa.fapesp.br\/?p=397763"},"modified":"2021-07-19T14:59:51","modified_gmt":"2021-07-19T17:59:51","slug":"lethal-networks","status":"publish","type":"post","link":"https:\/\/revistapesquisa.fapesp.br\/en\/lethal-networks\/","title":{"rendered":"Lethal networks"},"content":{"rendered":"<p><a href=\"https:\/\/revistapesquisa.fapesp.br\/wp-content\/uploads\/2021\/07\/003_Fotolab_303-0-1140-1.jpg\"><img decoding=\"async\" class=\"vertical\" src=\"https:\/\/revistapesquisa.fapesp.br\/wp-content\/uploads\/2021\/07\/003_Fotolab_303-0-1140-1.jpg\" alt=\"\" \/><\/a>Faced with an invasion of viruses or bacteria, human immune system cells sometimes overreact in a process known as NETosis, which has been shown to be more severe when the invader is SARS-CoV-2. \u201cThe nuclei, highlighted in blue in the image, are usually round,\u201d explains pharmacologist Fl\u00e1vio Prot\u00e1sio Veras. &#8220;During NETosis, they look elongated because of the networks of DNA being released from the cells.\u201d The red and green dots are proteins that attach to these networks and exacerbate the process, which in COVID-19 patients can cause damage to the lungs and even death. In his research, Veras is looking for drugs that can minimize this damage.<\/p>\n<p><em>Image submitted by Fl\u00e1vio Prot\u00e1sio Veras, a researcher on a postdoctoral fellowship at the Ribeir\u00e3o Preto Medical School of the University of S\u00e3o Paulo<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"Faced with an invasion of viruses or bacteria, human immune system cells sometimes overreact in a process known as NETosis, which has been shown to be more severe when the invader is SARS-CoV-2","protected":false},"author":475,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[164],"tags":[210,242],"coauthors":[785],"class_list":["post-397763","post","type-post","status-publish","format-standard","hentry","category-photolab","tag-cellular-biology","tag-immunology","keywords-coronavirus-en","keywords-coronavirus-en-2","keywords-covid-19-en","keywords-sars-cov-2-en","keywords-sars-cov-2-en-2","keywords-virology"],"acf":[],"_links":{"self":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/397763","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/users\/475"}],"replies":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/comments?post=397763"}],"version-history":[{"count":4,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/397763\/revisions"}],"predecessor-version":[{"id":401816,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/397763\/revisions\/401816"}],"wp:attachment":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/media?parent=397763"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/categories?post=397763"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/tags?post=397763"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/coauthors?post=397763"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}