{"id":462819,"date":"2022-12-13T16:20:34","date_gmt":"2022-12-13T19:20:34","guid":{"rendered":"https:\/\/revistapesquisa.fapesp.br\/?p=462819"},"modified":"2022-12-13T16:20:34","modified_gmt":"2022-12-13T19:20:34","slug":"organs-partially-revived","status":"publish","type":"post","link":"https:\/\/revistapesquisa.fapesp.br\/en\/organs-partially-revived\/","title":{"rendered":"Organs partially revived"},"content":{"rendered":"<p>Scientists at Yale University in the USA partially revived cells in several pig organs an hour after the animals&#8217; hearts stopped beating. A team led by neuroscientist Nenad Sestan achieved the feat by pumping a fluid rich in oxygen, nutrients, and protective compounds through the animals&#8217; circulatory system. The technology developed by the Yale group uses perfusion\u2014similar to equipment that can function as a person\u2019s heart and lungs during surgery\u2014to pump a solution they formulated called OrganEx through the body. Sestan&#8217;s team successfully restored cell function in organs such as the heart, kidneys, and liver for up to six hours\u2014signs of electrical activity were detected in the heart, for example (<em>Nature<\/em>, August 3). In 2019, the group partially revived pig brains four hours after death (<a href=\"https:\/\/revistapesquisa.fapesp.br\/en\/partially-revived-brains\/\" target=\"_blank\" rel=\"noopener\"><em>see<\/em> Pesquisa FAPESP <em>issue<\/em> <\/a><em><a href=\"https:\/\/revistapesquisa.fapesp.br\/en\/partially-revived-brains\/\">n\u00ba 279<\/a>)<\/em>. The scientists envision a number of potential applications, including prolonging the life of organs for transplantation and restoring tissues damaged by heart attacks and strokes.<\/p>\n","protected":false},"excerpt":{"rendered":"Experiment revives pig organ cells up to an hour after the heart stopped beating","protected":false},"author":475,"featured_media":462820,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[1651],"tags":[250],"coauthors":[785],"class_list":["post-462819","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-notes","tag-neuroscience"],"acf":[],"_links":{"self":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/462819","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/users\/475"}],"replies":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/comments?post=462819"}],"version-history":[{"count":1,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/462819\/revisions"}],"predecessor-version":[{"id":462824,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/posts\/462819\/revisions\/462824"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/media\/462820"}],"wp:attachment":[{"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/media?parent=462819"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/categories?post=462819"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/tags?post=462819"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/revistapesquisa.fapesp.br\/en\/wp-json\/wp\/v2\/coauthors?post=462819"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}