Medicine

GOOD PRACTICES

Under the skin

University investigates and apologizes for unethical dermatology tests conducted on prison inmates in the 1960s and 1970s

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RESEARCH ITINERARIES

From the lab to the field

An encounter with a community in rural Goiás transformed biologist Carlos Menck’s perspective on genetics

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RETROSPECT

The science rebel

Credited with discovering bradykinin, Maurício Oscar da Rocha e Silva fought to overcome the narrow-mindedness within scientific institutions before his death 40 years ago

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INTERVIEW

Chi Van Dang: An optimistic view of oncology

Scientific director of the Ludwig Institute for Cancer Research talks about the challenges and perspectives of the field

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Infectious diseases

Antibody neutralizes Zika in preclinical trials

A superpotent immunoglobulin M antibody stopped the virus in animal tests

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COVID-19

Strains of the Omicron variant lead to dramatic rise in COVID-19 cases at the end of 2022

Average weekly number of new infections increased 12-fold between November and mid-December, with 4.6 times as many deaths

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INTERVIEW

Carmino Antonio de Souza: The ways of healthcare

UNICAMP hematologist helps develop a plan to resume production of essential drugs, an imperative created by the COVID-19 pandemic

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COVER

Science with the public

People without academic experience contribute to data collection and knowledge production

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COVID-19

The performance of COVID-19 preprints

Half of COVID-19 preprints uploaded in 2020 were later accepted for publication

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photolab

Roots of life

Hormone treatment for superovulation in cattle induces proliferation of blood vessels

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INFORMATION TECHNOLOGY

Artificial intelligence in healthcare

AI-based technologies are already being used in medicine, but there are hurdles still to overcome before they can be incorporated on a larger scale in Brazil

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Health

The falling cost of DNA sequencing and our increasing ability to interpret data are bringing genetic testing closer to clinical practice

DNA analysis is already being used to diagnose rare diseases and guide cancer treatment

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Acknowledgment

Professor Emeritus at USP in Ribeirão

Marco Antonio Zago, president of FAPESP, is named professor emeritus at USP in Ribeirão Preto

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RESEARCH ITINERARIES

Life shows the way

The choices that led cardiologist Maria Cristina Izar back to scientific research

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BIOETHICS

Controversies in genetic editing

Advances in medical treatments using CRISPR gene editing demand the establishment of governance mechanisms to guarantee equal access

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NOBEL PRIZE

The 2022 winners

Twelve individuals and two institutions were awarded the Nobel Prize this year

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ENGINEERING

A robotic guide dog

Startup from Espírito Santo pre-launches autonomous machine to help visually impaired people navigate closed spaces

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Biotechnology

Cell therapy on the radar

Company changes business plan and invests in regenerative medicine in search of a cure for diseases that currently have no treatment

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EPIDEMIOLOGY

Deaths from breast and cervical cancer on the rise in the state of São Paulo

Numbers began to increase in 2016 after more than a decade of decline

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Public health

The high economic cost of Zika in Brazil

Families of children diagnosed with Congenital Zika Syndrome—which includes microcephaly—face high medical expenses, partly covered by the government

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Chemistry

Artificial cornea restores vision

Patients in Iran and India able to see better thanks to bioengineered implant

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COVID-19

Nanobridges used by virus to infect neurons

The coronavirus induces the formation of nanotubes between infected and uninfected neurons, thus spreading through the central nervous system

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GOOD PRACTICES

Articles by Nobel Prize winner retracted

Articles by Nobel Prize winner retracted

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Health

The spread of monkeypox

Cases worldwide increased 20% in one week; Brazil is the country with the third-highest number of infections

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PUBLIC POLICIES

A method to overcome the vicious cycle of poverty

With multiple evidence-based actions, the Dara Institute model can inspire state public policy

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Cover

E-cigarettes cause lung condition known as EVALI

Substances in the vapor produced by e-cigarettes can cause damage similar to the effects of COVID-19

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COVER

Almost one million Brazilians regularly use e-cigarettes

Despite being banned in the country, the devices are used by many young people aged 18 to 34

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ACKNOWLEDGMENT

New member of the Board of Trustees

Infectious disease specialist David Uip is the newest member of FAPESP's Board of Trustees

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MEDICINE

The resurgence of the Sabiá virus

Two new cases of Brazilian hemorrhagic fever, caused by the Sabiá virus, have been identified

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Public health

Number of unvaccinated children rises

Brazil was one of the countries most affected by falling childhood vaccination in 2021

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