Marcos Pivetta and Ricardo Zorzetto

Science

Antonio Bianco: An adjustment to hypothyroidism treatment

The Brazilian physician based in the USA explains how he discovered that current hormone therapy could fail and proposes a correction to its use

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XENOTRANSPLANTATION

A team from USP is attempting to create genetically modified pigs to provide organs to humans

The animals will be raised in special facilities, such as one opened on the Cidade Universitária campus in April

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Epidemiology

The mental burden of the young

Frequency of psychiatric disorders doubles between end of infancy and start of adolescence

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Interview

Carlos Augusto Monteiro: The normality of being overweight

USP epidemiologist studying the effects of nutrition on health attributes the rise in obesity to the transformation of the food system

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Interview

Luis Bahamondes: The paradoxes of women’s health

The specialist in methods of contraception warns about the importance of long-lasting forms of birth control for reducing the risk of unplanned pregnancy and abortion

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Neurology

Study identifies rare form of Alzheimer’s acquired through treatment no longer used

Individuals were given a hormone extracted from cadavers, contaminated with protein fragments associated with the onset of the disease

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Interview

2024 could become the year with the highest number of dengue cases

FAMERP virologist Maurício Nogueira discusses the characteristics of the current epidemic and the need for the health system to prepare for more patients

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Pediatrics

Anemia and nutrient deficiencies fall while being overweight increases among children up to 5 years old

A nationwide study also found that ultra-processed foods are consumed at a high frequency

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Cover

Testing of candidate antibiotics has increased in the last decade

The number of compounds entering clinical use is still too low to combat multidrug-resistant bacteria

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Cover

Antibiotic-resistant bacteria on the rise in Brazilian hospitals

Microorganisms killed at least 33,000 people in the country in 2019

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Medicine

Study determines the route of eggs imported to Brazil

The tortuous path of human eggs exported from Spain to Brazil

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BIOLOGY

Yellow fever virus has been circulating uninterrupted in southern Brazil for seven years

The disease vector arrived in the country’s southeast two to three years earlier than previously thought

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IMMUNOLOGY

Studies identify actions of immune cells that harm the body during sepsis

Erroneous response by the immune system as a result of an infection affects 420,000 people per year in Brazil and kills 230,000

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INTERVIEW

Elisabete Weiderpass: Waiting for a tsunami

Director of the WHO’s International Agency for Research on Cancer warns of an expected increase in cases in the coming decades

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INTERVIEW

Celso Grebogi: The chaos tamer

Physicist from Curitiba creates strategies to intervene in complex systems such as the climate and ecological networks

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COVER

At least 1.76 million people in Brazil suffer from dementia

The number of cases of the disease is increasing as the population ages and could reach 5.5 million by 2050

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Ophthalmology

Biochemists identify retinal changes associated with blindness in preterm infants

Abnormal blood vessel formation affects the availability and utilization of lipids that constitute cell membranes

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Cover

The hidden damage of rape

Sexual violence causes psychological distress and results in inflammation that can accelerate ageing

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Immunology

Antibodies defeat yellow fever in animals

Rodents and monkeys given an infusion of the compounds were able to survive infection

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NEUROSCIENCE

Learning to tell time

Neurons from one region of the brain train those from another to count the ticking of seconds

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Public health

One in seven 40-year-old Brazilian women has intentionally terminated at least one pregnancy

Half of them had abortions between the ages of 12 and 19

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Genetics

Natural defense against Chagas

Genetic alteration capable of protecting people from the disease spread among native peoples of the Amazon 7,500 years ago

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Oncology

Vaccine candidate designed to treat cancer caused by HPV

In experiments on rodents, vaccine formulations eliminated tumors and rid the animals of the disease for a long time

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Neurosciences

Brazilian and French researchers identify a new possible biological cause for depression

Failure to recycle neuron components leads to signs of the disease in mice similar to those seen in humans

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Ecology

The reason behind the megadiversity of fish in South America

Geological events of the last 55 million years have restructured hydrographic basins and contributed to the diversification of freshwater species

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IMMUNOLOGY

Butantan’s dengue vaccine is 80% effective

The vaccine offered protection against two serotypes of the virus in the final phase of human trials

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IMMUNOLOGY

Construction begins on Brazil’s new National Vaccine Center in Belo Horizonte

The institution will function as a link between basic immunobiological research and final products

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COVID-19

Nearly 60,000 people in China died of COVID-19 in one month

After weeks of no information, the Asian giant released more plausible data in January on the total number of deaths caused by the current outbreak

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INTERVIEW

Mercedes Bustamante: Before the water runs out

Biologist from the University of Brasília warns that deforestation in the Cerrado also harms other regions

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INTERVIEW

Chi Van Dang: An optimistic view of oncology

Scientific director of the Ludwig Institute for Cancer Research talks about the challenges and perspectives of the field

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