Ricardo Zorzetto

INTERVIEW

Celso Grebogi: The chaos tamer

Physicist from Curitiba creates strategies to intervene in complex systems such as the climate and ecological networks

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COVER

At least 1.76 million people in Brazil suffer from dementia

The number of cases of the disease is increasing as the population ages and could reach 5.5 million by 2050

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Ophthalmology

Biochemists identify retinal changes associated with blindness in preterm infants

Abnormal blood vessel formation affects the availability and utilization of lipids that constitute cell membranes

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Cover

The hidden damage of rape

Sexual violence causes psychological distress and results in inflammation that can accelerate ageing

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Immunology

Antibodies defeat yellow fever in animals

Rodents and monkeys given an infusion of the compounds were able to survive infection

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NEUROSCIENCE

Learning to tell time

Neurons from one region of the brain train those from another to count the ticking of seconds

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Public health

One in seven 40-year-old Brazilian women has intentionally terminated at least one pregnancy

Half of them had abortions between the ages of 12 and 19

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Genetics

Natural defense against Chagas

Genetic alteration capable of protecting people from the disease spread among native peoples of the Amazon 7,500 years ago

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Oncology

Vaccine candidate designed to treat cancer caused by HPV

In experiments on rodents, vaccine formulations eliminated tumors and rid the animals of the disease for a long time

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Neurosciences

Brazilian and French researchers identify a new possible biological cause for depression

Failure to recycle neuron components leads to signs of the disease in mice similar to those seen in humans

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Ecology

The reason behind the megadiversity of fish in South America

Geological events of the last 55 million years have restructured hydrographic basins and contributed to the diversification of freshwater species

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IMMUNOLOGY

Butantan’s dengue vaccine is 80% effective

The vaccine offered protection against two serotypes of the virus in the final phase of human trials

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IMMUNOLOGY

Construction begins on Brazil’s new National Vaccine Center in Belo Horizonte

The institution will function as a link between basic immunobiological research and final products

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COVID-19

Nearly 60,000 people in China died of COVID-19 in one month

After weeks of no information, the Asian giant released more plausible data in January on the total number of deaths caused by the current outbreak

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INTERVIEW

Mercedes Bustamante: Before the water runs out

Biologist from the University of Brasília warns that deforestation in the Cerrado also harms other regions

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INTERVIEW

Chi Van Dang: An optimistic view of oncology

Scientific director of the Ludwig Institute for Cancer Research talks about the challenges and perspectives of the field

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COVID-19

Strains of the Omicron variant lead to dramatic rise in COVID-19 cases at the end of 2022

Average weekly number of new infections increased 12-fold between November and mid-December, with 4.6 times as many deaths

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OBITUARY

Research as a passion and a mission

Herch Moysés Nussenzveig, a scholar of optical phenomena such as the rainbow, defender of science, and physics education enthusiast, died in November, at the age of 90

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Health

The falling cost of DNA sequencing and our increasing ability to interpret data are bringing genetic testing closer to clinical practice

DNA analysis is already being used to diagnose rare diseases and guide cancer treatment

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IMMUNOLOGY

Three Brazilian COVID-19 vaccines begin human testing

The three candidates use different technologies; two have already completed the first phase of clinical trials

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The rise and fall of Tupi

The rise and fall of Tupi

Speakers of the language may have numbered 4 to 5 million a millennium ago but began declining sharply before Europeans arrived on the continent

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Cover

Sexual violence causes psychological distress and results in inflammation that can accelerate aging

UNIFESP study characterized the effects of rape on women and girls in the city of São Paulo

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NUTRITION

Foods high in sugar, sodium, and saturated fats will have to display a warning on the label

Companies will have at least 12 months to adapt to the new labeling rules, which include changes to the nutritional information table

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Health

Postmortem analysis identifies brain lesions in individuals who developed depression as adults

Study involved samples from 741 men and women aged 60 to 84 stored in USP’s Biobank for Studies on Aging

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ARCHAEOLOGY

Dating indicates that skeleton found in Piauí is 9,600 years old

Nicknamed Zuzu, the individual was a contemporary of the oldest human groups in South America

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NEUROSCIENCE

Study maps brain evolution over a lifetime

Collection of MRI images shows that the organ grows rapidly in the first three years of life and slowly declines during adulthood

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MEDICINE

Children with Congenital Zika Syndrome suffer developmental delays in motor, cognitive, and language skills

Neurological damage caused by the virus impairs the ability to move, learn, and talk

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BIOGEOGRAPHY

Water from the Amazon River separates Brazilian and Caribbean marine species

A sediment plume from the river penetrates thousands of kilometers into the Atlantic, home to its own fauna that differs to other regions of the ocean

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INTERVIEW

Margareth Dalcolmo: Pandemic scars

The physician-researcher discusses the difficulties faced by health professionals dealing with Covid-19, the dramatic struggles of patients she attended, and the likelihood of an increase in tuberculosis cases in the coming years

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INFECTIOUS DISEASES

A long-sought cure may be closer

Experimental treatment able to control HIV for six months after stopping antiretrovirals

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