Genetics

GENOMICS

Primate genetic material could contribute to precision medicine

International project is sequencing the DNA of more than 200 species in pursuit of tools to predict human propensity to diseases

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ZOOLOGY

Zoonomia project compares genomes in search of answers about evolution and health

Analysis of an unprecedented volume of data could provide insights into human diseases

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INTERVIEW

Marcio de Castro: A boost for bold research

New scientific director shares his vision for science and the future of FAPESP and reflects on his career as a plant geneticist

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Microbiology

Viruses that infect insects increase the ability of Aedes aegypti to transmit diseases to humans

Mosquitoes infected with both PCLV and HTV are three times more likely to carry the dengue virus

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Computer science

Synthetic DNA could be used to store digital data

Device inspired by the molecule that stores our genetic code will lead to the miniaturization of storage media and ensure data integrity for a much longer time

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Genetics

Natural defense against Chagas

Genetic alteration capable of protecting people from the disease spread among native peoples of the Amazon 7,500 years ago

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Genetics

Same people, different origins

Genome analysis of 51 individuals of the Ashaninka indigenous people from the Peruvian and Brazilian Amazon identifies two distinct groups

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Genetics

Risks of gene editing in babies

Using CRISPR-Cas9 and other gene-editing tools to create babies without genetic anomalies not yet on the horizon

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Biodiversity

The climate, a driver of diversification

Regional rainfall patterns can be a decisive factor in plant diversification

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Biotechnology

Transgenic Aedes aegypti mosquitoes hit the market

Brazil is the first country to authorize general sale of the genetically modified mosquito

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Biotechnology

Company develops transgenic moth

New technology offers an alternative method to combat the biggest threat to maize crops

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Health

Unique genetic varieties of malaria-carrying parasite in Brazil

Brazilian varieties of Plasmodium vivax are distinct from each other and from those found in other countries

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RESEARCH ITINERARIES

From the lab to the field

An encounter with a community in rural Goiás transformed biologist Carlos Menck’s perspective on genetics

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INTERVIEW

Chi Van Dang: An optimistic view of oncology

Scientific director of the Ludwig Institute for Cancer Research talks about the challenges and perspectives of the field

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Acknowledgment

End of year award

Pesquisa FAPESP received Synapsis and IMPA Journalism Awards in 2022

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Health

The falling cost of DNA sequencing and our increasing ability to interpret data are bringing genetic testing closer to clinical practice

DNA analysis is already being used to diagnose rare diseases and guide cancer treatment

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BIOETHICS

Controversies in genetic editing

Advances in medical treatments using CRISPR gene editing demand the establishment of governance mechanisms to guarantee equal access

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NOBEL PRIZE

The 2022 winners

Twelve individuals and two institutions were awarded the Nobel Prize this year

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The rise and fall of Tupi

The rise and fall of Tupi

Speakers of the language may have numbered 4 to 5 million a millennium ago but began declining sharply before Europeans arrived on the continent

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COVID-19

Brazilian networks keep a close eye on coronavirus variants

SARS-CoV-2 genomic surveillance in the country backed by funding from British government program

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HISTORY

Possible origin of the Black Death

Black Death may have originated in the region of Eurasia that is now Kyrgyzstan, west of China

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DATA SCIENCE

The machines that make biology a science of huge numbers

DNA sequencers, recorders, drones, and other devices are increasingly being used to save time and shake up research methodologies

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Genetics

Mutations raise schizophrenia risk

Studies show that mutations can increase the risk of schizophrenia

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Crispr-Cas9

Disputed Crispr patents

Patents related to CRISPR-Cas9 use to edit the genes of plant and animal cells belong to the Broad Institute

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INFECTIOUS DISEASES

A long-sought cure may be closer

Experimental treatment able to control HIV for six months after stopping antiretrovirals

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ZOOLOGY

Hibernation delays aging in marmots and encourages sexual maturation in ground squirrels

Studies on the effects of hibernation were carried out by Brazilian researchers in the USA

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Primatology

The name of the monkey

DNA analysis confirms the species of pygmy marmoset given to naturalist Spix by indigenous people in the Amazon two centuries ago

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Genetics

A connection between big and small

Dog breeds can have up to 40-fold size differences, determined by 25 genes

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Careers

Healthy innovation

Researcher from Minas Gerais recognized for studies on diagnosis and prevention of infectious diseases

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Zoology

DNA in the air helps identify animals

Two studies published in the same scientific journal in January indicate that the air contains DNA at levels sufficient to allow species identification

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