Francisco Bicudo and Ricardo Zorzetto
Primary immunodeficiencies

When the thymus gland is unwell
Extra copy of the gene harms the cells that defend against Down syndrome
By Francisco Bicudo and Ricardo Zorzetto
Insulin resistance

Visceral connections
Change in the intestinal microbiota profile favors diabetes and obesity
Walter Neves

Walter Neves: Luzia’s father
Archeologist developed a theory on man’s arrival to the Americas
By Marcos Pivetta and Ricardo Zorzetto
Oncological therapy

Another solution
Combined treatment may avoid radical surgery for rectal cancer
Interview

The enigma of pluripotency
Controlling the differentiation process of human embryonic stem cells
By Marcos Pivetta and Ricardo Zorzetto
Neurodegenerative Diseases

Interrupted communication
Blocking of chemical signal could result in Alzheimer’s disease treatment
Mauricio da Rocha e Silva

Mauricio da Rocha e Silva: The secret of visibility
How to produce an international scientific journal
By Neldson Marcolin and Ricardo Zorzetto
Primate life

The matriarchs of the forest
Coexistence with the mother increases the reproductive success of muriquis
Cardiac hypertrophy

The heart’s sensor
An enzyme makes cells expand and opens the way to cardiac insufficiency
Immunology

Allergies make us moody
More than a mere irritation, too much sensitivity to foods may cause anxiety
Mineralogy

The past in grains of sand
Radioactive material allows to track the geological origin of the beaches
Cover

American inheritance
Indigenous groups share a genetic alteration that favors obesity and diabetes
Physics

Restless neighborhood
Strategy allows evaluation of the magnetic interaction between nanoparticles
Endocrinology

Sudden immobility
Genetic alteration may paralyse the limbs of people with hyperthyroidism
Astrophysics

The Sun and its sisters
Brazilians identify stars similar to the one that warms and lights up the Earth