Immunology

IMMUNOLOGY

Butantan’s dengue vaccine is 80% effective

The vaccine offered protection against two serotypes of the virus in the final phase of human trials

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IMMUNOLOGY

Construction begins on Brazil’s new National Vaccine Center in Belo Horizonte

The institution will function as a link between basic immunobiological research and final products

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OBITUARY

Defender of access to science

Biochemist Isaías Raw produced internationally relevant research, actively disseminated knowledge, and contributed to the production of vaccines and immunobiologicals

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INTERVIEW

Chi Van Dang: An optimistic view of oncology

Scientific director of the Ludwig Institute for Cancer Research talks about the challenges and perspectives of the field

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IMMUNOLOGY

Three Brazilian COVID-19 vaccines begin human testing

The three candidates use different technologies; two have already completed the first phase of clinical trials

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Ecology

Vaccinating primates against yellow fever

Early trials suggest human vaccines are effective in wild primate species susceptible to the yellow fever virus

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Public health

The high economic cost of Zika in Brazil

Families of children diagnosed with Congenital Zika Syndrome—which includes microcephaly—face high medical expenses, partly covered by the government

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photolab

Narrow passage

Image shows how Leukocytes squeeze through tiny pores

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Ecology

Vaccinating primates against yellow fever

Early trials suggest human vaccines are effective in wild primate species susceptible to the yellow fever virus

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COVID-19

The quest for a Brazilian vaccine

Researchers are testing a range of technologies, but few initiatives will receive the funding needed for costly phase 3 clinical trials

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Covid-19

Vaccines generate more consistent immune response

The immune response to the novel coronavirus provided by vaccines is more consistent than that triggered by natural infection with SARS-CoV-2

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COVID-19

Two vaccines safe for children

The CoronaVac vaccine, produced in Brazil by the Butantan Institute, is safe for children and adolescents, with no major side effects

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HEALTH

Pioneering immunization

Malaria vaccine recommended for children in Africa by the WHO is the first to protect humans from a parasite

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Covid-19

Confidence in vaccines

Vaccination rate in Brazil greater than in developed countries

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COVID-19

Vaccination in decline

The COVID-19 vaccination pace has been decreasing worldwide

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Covid-19

Fewer vaccines for those who want them

In low- and middle-income countries the proportion of people who want to get vaccinated is considerably higher than in richer countries

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COVID-19

Universal vaccine

Researchers are trying to develop a broad-spectrum vaccine capable of protecting people against all types of coronaviruses and their variants

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COVID-19

Mixed protection

Preliminary studies suggest that combining two different vaccines could be useful in the fight against the pandemic

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COVID-19

All eyes on ButanVac

New vaccine candidate uses a more stable version of the spike protein

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COVID-19

Two vaccines prevent infection by Sars-CoV-2

Pfizer-BioNTech and Moderna vaccines are 80% effective at preventing SARS-Cov-2 infections after the first dose and 90% after the second

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COVID-19

Superior immunity

Studies of blood and tissue samples taken before the COVID-19 pandemic may help explain why the disease is more common and more severe in adults than in children

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photolab

Lethal networks

Faced with an invasion of viruses or bacteria, human immune system cells sometimes overreact in a process known as NETosis, which has been shown to be more severe when the invader is SARS-CoV-2

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COVID-19

New vaccines on the way

Butantan Institute and federal government plan to start human trials of two vaccine candidates in the coming months

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INTERVIEW

Eurico Arruda: Admirer of viruses

Coronavirus specialist and USP physician speaks about the new variants of SARS-CoV-2 and the risk they represent in the efficacy of some vaccines

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Covid-19

The expected effect of vaccines

Administering vaccines on a large scaled will tell us whether, in addition to protecting against the disease, they are also able to prevent infection by SARS-CoV-2

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Covid-19

Obstacle course

Research centers working on vaccines for the novel coronavirus in Brazil face major hurdles

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Covid-19

Antibodies reduce deaths

A clinical trial led by researchers at the University of Oxford, UK, identified a second drug capable of reducing mortality among patients with severe COVID-19

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Public health

Vaccinations have prevented 37 million deaths in 98 countries

Immunization against major diseases has had a significant impact on public health in low- and middle-income countries, helping to save 37 million lives between 2000 and 2019

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INTERVIEW

Dimas Covas: The trajectory of Butantan

The hematologist from USP readies the São Paulo institute to fight the pandemic and has plans to transform it into one of the world’s top producers of vaccines and serums

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COVID-19

vaccine. Now what?

The introduction of vaccines in the battle against the COVID-19 pandemic raises new challenges

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