Pharmacology

Immunology

Butantan vaccine candidate reduces the risk of severe dengue fever by 89%

The compound proved safe and prevented 67.3% of those immunized from developing symptoms of the disease

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Interview

Bruno Geloneze: Injections alone will not solve the problem

New anti-obesity drugs work well, says UNICAMP endocrinologist, but they need to be combined with a good diet and exercise to produce lasting benefits

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Pharmacology

The cannabinoid tree

Jamaican nettletree produces cannabinoids, like cannabis

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BIOTECHNOLOGY

Scientists develop serum for Africanized bee venom

Scientists develop serum for Africanized bee venom

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ETHICS

New rules for research involving human beings

New law set to come into force at the end of August will allow trials to be approved by a single body

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Public health

Anti-HIV medication still poorly distributed

Distribution of preventive HIV medicine concentrated in major cities

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Pharmacology

No-needle blood test

Just for women: new needle-free blood sugar test

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Public health

Shorter treatment for malaria

New drug proves as effective at preventing recurrences as current medications with longer courses

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Interview

2024 could become the year with the highest number of dengue cases

FAMERP virologist Maurício Nogueira discusses the characteristics of the current epidemic and the need for the health system to prepare for more patients

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Pharmacology

Reinforcement against rabies

Experimental synthetic drug evaluated as alternative means of fighting the human rabies virus

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Medicine

Spiders, allies of men

The Brazilian wandering spider serves as inspiration for erectile dysfunction drug

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INTERVIEW

David MacMillan: A catalyst for discoveries

Chemist won the Nobel Prize in 2021 for important innovations in the pharmaceutical industry

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PHARMACOLOGY

A potential vaccine against cocaine abuse

Vaccine stimulates the production of antibodies against cocaine in animal experiments

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Medicine

Medicinal cannabis seeds on sale in Argentina

Medicinal cannabis seeds approved for sale in Argentina

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Pharmacology

Psychedelics act against depression by stimulating connections between neurons

Antidepressant effect occurs independently of the mechanism that alters perception of reality

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COVID-19

Setbacks in coronavirus drug development

Health agencies are suspending the use of drugs that have lost efficacy against circulating variants of SARS-CoV-2

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Health

More powerful sunscreens

Antioxidant rosmarinic acid improves blocking of ultraviolet rays in sunscreen

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COVID-19

Thai version of vaccine similar to ButanVac induces good immune response

In phase 1 trials involving 210 people, the low-cost formulation produced more neutralizing antibodies than the Pfizer / BioNTech vaccine

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IMMUNOLOGY

Butantan’s dengue vaccine is 80% effective

The vaccine offered protection against two serotypes of the virus in the final phase of human trials

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IMMUNOLOGY

Construction begins on Brazil’s new National Vaccine Center in Belo Horizonte

The institution will function as a link between basic immunobiological research and final products

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Health

Immune cells increase pain from nerve damage

Immune cells increase chronic pain from nerve damage

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RETROSPECT

The science rebel

Credited with discovering bradykinin, Maurício Oscar da Rocha e Silva fought to overcome the narrow-mindedness within scientific institutions before his death 40 years ago

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IMMUNOLOGY

Three Brazilian COVID-19 vaccines begin human testing

The three candidates use different technologies; two have already completed the first phase of clinical trials

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Chemistry

Collaboration to fight drug resistance

Seven pharmaceutical companies pledge to share surveillance data on antimicrobial resistance

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PUBLIC SPENDING

SUS to save money as patent extensions come to an end

Expenditure on nine drugs could be reduced by R$3.9 billion, according to UFRJ estimates

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COVID-19

Anti-coronavirus semiconductors

Nanotechnological materials emerge as promising alternatives in the battle against SARS-CoV-2 and future pandemics

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photolab

Light sensors

In the lab, zebrafish larvae become covered in green glowing dots when exposed to certain drugs or pollutants

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Health

Nasal COVID-19 vaccine

Research into intranasal vaccines against Covid-19 is advancing

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COVID-19

Another step towards a universal vaccine

Clinical trials begin for broad-spectrum vaccines designed to offer protection against multiple coronaviruses

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COVID-19

New coronavirus drugs

Pharmaceuticals announce orally administered drugs designed to treat the disease caused by SARS-Cov-2

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