Pharmacology

COVID-19

Unequal access

Even before efficacy data for the vaccine candidates was released, it was clear that there will not be enough supply to immunize the entire global population before the end of next year

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COVID-19

Australia gives up on vaccine candidate

A vaccine being developed by the University of Queensland and biotechnology company CSL, both from Australia, is the first of more than 200 candidates to be discarded

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COVID-19

Vaccines and sharks

A compound extracted from the livers of sharks is used in five coronavirus vaccine candidates

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FIOCRUZ – 120 YEARS

A continuum of challenges

From the bubonic plague to Zika fever, the Oswaldo Cruz Foundation’s 120-year history has been punctuated by a succession of novel diseases and related discoveries

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FIOCRUZ – 120 YEARS

No rest on the anniversary

FIOCRUZ celebrates 120 years of public health literature, research, assistance, and teaching

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Cover

Vaccines edge closer

Less than a year after first cases of COVID-19 were confirmed, vaccine candidates in the final stages of development offer promising results

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COVID-19

Nasal spray prevents infection in ferrets

A nasal spray tested on ferrets prevented absorption of SARS-CoV-2 and for a period of 24 hours, prevented them from becoming infected with the novel coronavirus when exposed to animals known to be affected by the pathogen

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COVID-19

Stuttering progress

Advanced testing of COVID-19 vaccines continues at an accelerated pace, despite occasional interruptions caused by safety concerns

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Obituary

The pharmacy of plants

Elisaldo Carlini, a pioneer in the study of medicinal plants and cannabis compounds, dies at 90 years of age

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Innovation

A place in the sun

A thriving generics industry and government funding have helped to boost research and development spending among Brazilian pharmaceutical companies, study shows

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COVID-19

Study determines Chinese vaccine is safe

CoronaVac is safe and has no serious side effects

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COVID-19

Antibody treatment reduces time spent in hospital

American pharmaceutical company Eli Lilly presented the initial results of a clinical trial that used monoclonal antibodies in patients infected with the novel coronavirus

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Pharmacology

Schistosomiasis medicine

The US FDA has granted orphan drug status to the immunomodulator P-MAPA for use against schistosomiasis

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COVID-19

Intranasal coronavirus vaccine

Two international studies have suggested that COVID-19 aerosol vaccine candidates, administered intranasally, offer protection against SARS-CoV-2 infection in animals

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COVID-19

Vaccine tests advance

One of the best-known COVID-19 vaccine candidates achieved good results in the first phase of clinical trials

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Pharmacology

Lasting action against HIV

Researchers at American pharmaceutical company Gilead Sciences have published the results of clinical trials of a new long-acting antiretroviral against HIV

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Data

At least 125 COVID-19 vaccines are in development, with 10 already undergoing clinical trials

Vaccines in the clinical trials phase worldwide and in development in Brazil (as of May 27, 2020)

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Cover

Progress toward dengue vaccine

A formulation developed by the Butantan Institute has shown protective effects in the second phase of testing

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Cover

The antivirus arsenal

The search for an effective treatment for COVID-19 includes testing drugs already used against other diseases and even plasma

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Pharmacology

Monkeys are the best animal model

Monkeys appear to be the best animals for testing SARS-CoV-2 vaccines and drugs

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Pharmacology

Medicines from Cannabis

Based on its proven efficacy for epilepsy, cannabidiol has become the target of intensive research

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Video

Techniques in the search for a vaccine against Covid-19

Teams from several countries head projects seeking to produce imunizing agents in a short time

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Interview

João Batista Calixto: The voice of Brazilian pharmaceuticals

The pharmacologist from Minas Gerais has dedicated his life to developing new drugs

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Public health

The challenge of diagnosing Zika

There is no scientific consensus that any of the 48 approved laboratory tests can differentiate between Zika and the dengue virus

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Pharmacology

Personalized medication

Researchers in the USA have created a custom drug tailored specifically to an american girl with a rare and fatal genetic disorder

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Health

Life-saving vaccines

Butantan produces 100 million doses of nine vaccines each year

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Health

Partnership for a dengue vaccine

Butantan produces 100 million doses of nine different types each year

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Pharmacology

Material releases drug at regular intervals

An international group of researchers has developed a nanostructured material capable of releasing drugs in low concentrations at regular intervals

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Pharmacology

Remedy for menstrual cramps fights schistosomiasis

An anti-inflammatory widely used to alleviate menstrual cramps has been shown through animal testing to be effective at treating schistosomiasis

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Interview

Paola Marcella Camargo Minoprio: A new front against emerging diseases

The Pasteur Institute in Paris, USP, and FIOCRUZ start partnership under coordination of São Paulo biomedical scientist

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