Immunology

VIROLOGY

Study identifies how the Chikungunya virus causes death

Infectious agent causes dysregulated metabolism and inflammation in multiple organs, including the brain

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Immunology

Mechanism that keeps the immune response in check also aggravates malaria

The protozoan that causes the disease multiplies freely when certain immune cells are taken out of the fight

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Immunology

Cutaneous leishmaniasis may be aggravated by viral and bacterial coinfections

Cutaneous leishmaniasis may be aggravated by viral and bacterial coinfections

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Genetics

Chikungunya virus caused seven outbreaks in Brazil in 10 years

The agent that causes the disease has already been identified in 60% of municipalities

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BIOLOGY

Yellow fever virus has been circulating uninterrupted in southern Brazil for seven years

The disease vector arrived in the country’s southeast two to three years earlier than previously thought

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COVID-19

Nonpharmaceutical interventions helped reduce the impact of COVID-19

Nonpharmaceutical interventions helped reduce the impact of COVID-19

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EPIDEMIOLOGY

Falls in uptake of the MMR vaccine occurred at different rates between 2006 and 2020

The declines were greater in poorer municipalities and more intense during the economic crisis and the beginning of the COVID-19 pandemic

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IMMUNOLOGY

Studies identify actions of immune cells that harm the body during sepsis

Erroneous response by the immune system as a result of an infection affects 420,000 people per year in Brazil and kills 230,000

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PHARMACOLOGY

A potential vaccine against cocaine abuse

Vaccine stimulates the production of antibodies against cocaine in animal experiments

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Immunology

Antibodies defeat yellow fever in animals

Rodents and monkeys given an infusion of the compounds were able to survive infection

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COVID-19

Thai version of vaccine similar to ButanVac induces good immune response

In phase 1 trials involving 210 people, the low-cost formulation produced more neutralizing antibodies than the Pfizer / BioNTech vaccine

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Oncology

Vaccine candidate designed to treat cancer caused by HPV

In experiments on rodents, vaccine formulations eliminated tumors and rid the animals of the disease for a long time

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IMMUNOLOGY

Butantan’s dengue vaccine is 80% effective

The vaccine offered protection against two serotypes of the virus in the final phase of human trials

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IMMUNOLOGY

Construction begins on Brazil’s new National Vaccine Center in Belo Horizonte

The institution will function as a link between basic immunobiological research and final products

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OBITUARY

Defender of access to science

Biochemist Isaías Raw produced internationally relevant research, actively disseminated knowledge, and contributed to the production of vaccines and immunobiologicals

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INTERVIEW

Chi Van Dang: An optimistic view of oncology

Scientific director of the Ludwig Institute for Cancer Research talks about the challenges and perspectives of the field

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IMMUNOLOGY

Three Brazilian COVID-19 vaccines begin human testing

The three candidates use different technologies; two have already completed the first phase of clinical trials

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Ecology

Vaccinating primates against yellow fever

Early trials suggest human vaccines are effective in wild primate species susceptible to the yellow fever virus

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Public health

The high economic cost of Zika in Brazil

Families of children diagnosed with Congenital Zika Syndrome—which includes microcephaly—face high medical expenses, partly covered by the government

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photolab

Narrow passage

Image shows how Leukocytes squeeze through tiny pores

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Ecology

Vaccinating primates against yellow fever

Early trials suggest human vaccines are effective in wild primate species susceptible to the yellow fever virus

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COVID-19

The quest for a Brazilian vaccine

Researchers are testing a range of technologies, but few initiatives will receive the funding needed for costly phase 3 clinical trials

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Covid-19

Vaccines generate more consistent immune response

The immune response to the novel coronavirus provided by vaccines is more consistent than that triggered by natural infection with SARS-CoV-2

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COVID-19

Two vaccines safe for children

The CoronaVac vaccine, produced in Brazil by the Butantan Institute, is safe for children and adolescents, with no major side effects

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HEALTH

Pioneering immunization

Malaria vaccine recommended for children in Africa by the WHO is the first to protect humans from a parasite

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Covid-19

Confidence in vaccines

Vaccination rate in Brazil greater than in developed countries

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COVID-19

Vaccination in decline

The COVID-19 vaccination pace has been decreasing worldwide

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Covid-19

Fewer vaccines for those who want them

In low- and middle-income countries the proportion of people who want to get vaccinated is considerably higher than in richer countries

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COVID-19

Universal vaccine

Researchers are trying to develop a broad-spectrum vaccine capable of protecting people against all types of coronaviruses and their variants

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COVID-19

Mixed protection

Preliminary studies suggest that combining two different vaccines could be useful in the fight against the pandemic

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