Immunology

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The uncertainty of herd immunity

With a lack of scientific consensus on the subject, experts warn that protection measures against COVID-19 must be maintained

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Cover

The puzzle of immunity

Crucial questions about the response of the immune system to the novel coronavirus remain unanswered

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COVID-19

Vaccine tests advance

One of the best-known COVID-19 vaccine candidates achieved good results in the first phase of clinical trials

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INTERVIEW

Cristiana Toscano: An unprecedented global effort

According to the only Brazilian member of a WHO vaccine committee, we are experiencing unprecedented worldwide collaboration to develop a vaccine in record time

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COVER

Saving time

Brazilian research centers negotiate deals to import vaccine production technology

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Covid-19

Looking for shortcuts

International teams use eight different techniques to create 150 COVID-19 vaccine candidates in six months

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Predicting the course of epidemics

Mathematical modeling of infectious disease, a science perfected over the last 250 years, is helping guide the COVID-19 response through uncertainties

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The reality of data

Mapping and systematizing COVID-19 data is crucial to controlling the disease in Brazil

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Data

At least 125 COVID-19 vaccines are in development, with 10 already undergoing clinical trials

Vaccines in the clinical trials phase worldwide and in development in Brazil (as of May 27, 2020)

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Interview

Michel Nussenzweig: Antibody hunter

Brazilian-born immunologist searches the plasma of patients who have survived COVID-19 for proteins capable of fighting the novel coronavirus

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Progress toward dengue vaccine

A formulation developed by the Butantan Institute has shown protective effects in the second phase of testing

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The antivirus arsenal

The search for an effective treatment for COVID-19 includes testing drugs already used against other diseases and even plasma

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Science fights back

In just four months, 8,000 scientific articles have been published on Covid-19, more than 70 drugs tested against SARS-CoV-2, and the first vaccines trialed on humans

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Pharmacology

Monkeys are the best animal model

Monkeys appear to be the best animals for testing SARS-CoV-2 vaccines and drugs

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Data

Scientific research on coronavirus

The coronaviridae virus family encompasses approximately 40 known species

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Public health

Novel coronavirus in Brazil

The new coronavirus that emerged in China has arrived in the country, where four other less dangerous types already circulate

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Video

Techniques in the search for a vaccine against Covid-19

Teams from several countries head projects seeking to produce imunizing agents in a short time

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Public health

The challenge of diagnosing Zika

There is no scientific consensus that any of the 48 approved laboratory tests can differentiate between Zika and the dengue virus

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Health

Life-saving vaccines

Butantan produces 100 million doses of nine vaccines each year

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Health

Partnership for a dengue vaccine

Butantan produces 100 million doses of nine different types each year

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Medicine

Clean blood against yellow fever

Experimental plasma exchange therapy reduced mortality to 5% this year in São Paulo

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Interview

Paola Marcella Camargo Minoprio: A new front against emerging diseases

The Pasteur Institute in Paris, USP, and FIOCRUZ start partnership under coordination of São Paulo biomedical scientist

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Medicine

HIV therapy has prevented 9.5 million deaths

Antiretroviral therapy prevented 9.5 million deaths worldwide between 1995 and 2015, with a global economic benefit of US$1.05 trillion

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Public Health 

The end of the AIDS epidemic?

The US government wants to reduce new cases of AIDS by 90% by 2030, but faces the challenge of reaching vulnerable groups

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Public health

The fight against measles

The goal of eliminating the transmission of measles worldwide by 2020 is far from being achieved

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Health

Life-saving vaccines

Butantan produces 100 million doses of nine vaccines each year

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Health

Partnership for a dengue vaccine

A Butantan vaccine in final trials leads to a US$100 million agreement with a US pharma company

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Tropical diseases

A center for safeguarding health in the Amazon

Founded in 1936, the Evandro Chagas Institute produces world-leading research on infectious and parasitic diseases and environmental issues

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Interview

Pedro Fernando da Costa Vasconcelos: The return of yellow fever and Zika

Discoverer of more than 100 species of viruses in the Amazon, the virologist from the state of Pará says it's just a matter of time before there are new outbreaks of the two diseases

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The reasons for the decline in vaccinations

At least nine factors contribute to a reduction in childhood immunization and increase the risk of the reappearance of serious illnesses

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