Pharmacology

FIOCRUZ – 120 YEARS

No rest on the anniversary

FIOCRUZ celebrates 120 years of public health literature, research, assistance, and teaching

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Cover

Vaccines edge closer

Less than a year after first cases of COVID-19 were confirmed, vaccine candidates in the final stages of development offer promising results

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COVID-19

Nasal spray prevents infection in ferrets

A nasal spray tested on ferrets prevented absorption of SARS-CoV-2 and for a period of 24 hours, prevented them from becoming infected with the novel coronavirus when exposed to animals known to be affected by the pathogen

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COVID-19

Stuttering progress

Advanced testing of COVID-19 vaccines continues at an accelerated pace, despite occasional interruptions caused by safety concerns

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Obituary

The pharmacy of plants

Elisaldo Carlini, a pioneer in the study of medicinal plants and cannabis compounds, dies at 90 years of age

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Innovation

A place in the sun

A thriving generics industry and government funding have helped to boost research and development spending among Brazilian pharmaceutical companies, study shows

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COVID-19

Study determines Chinese vaccine is safe

CoronaVac is safe and has no serious side effects

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COVID-19

Antibody treatment reduces time spent in hospital

American pharmaceutical company Eli Lilly presented the initial results of a clinical trial that used monoclonal antibodies in patients infected with the novel coronavirus

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Pharmacology

Schistosomiasis medicine

The US FDA has granted orphan drug status to the immunomodulator P-MAPA for use against schistosomiasis

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COVID-19

Intranasal coronavirus vaccine

Two international studies have suggested that COVID-19 aerosol vaccine candidates, administered intranasally, offer protection against SARS-CoV-2 infection in animals

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COVID-19

Vaccine tests advance

One of the best-known COVID-19 vaccine candidates achieved good results in the first phase of clinical trials

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Pharmacology

Lasting action against HIV

Researchers at American pharmaceutical company Gilead Sciences have published the results of clinical trials of a new long-acting antiretroviral against HIV

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Data

At least 125 COVID-19 vaccines are in development, with 10 already undergoing clinical trials

Vaccines in the clinical trials phase worldwide and in development in Brazil (as of May 27, 2020)

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Cover

Progress toward dengue vaccine

A formulation developed by the Butantan Institute has shown protective effects in the second phase of testing

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Cover

The antivirus arsenal

The search for an effective treatment for COVID-19 includes testing drugs already used against other diseases and even plasma

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Pharmacology

Monkeys are the best animal model

Monkeys appear to be the best animals for testing SARS-CoV-2 vaccines and drugs

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Pharmacology

Medicines from Cannabis

Based on its proven efficacy for epilepsy, cannabidiol has become the target of intensive research

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Video

Techniques in the search for a vaccine against Covid-19

Teams from several countries head projects seeking to produce imunizing agents in a short time

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Interview

João Batista Calixto: The voice of Brazilian pharmaceuticals

The pharmacologist from Minas Gerais has dedicated his life to developing new drugs

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Public health

The challenge of diagnosing Zika

There is no scientific consensus that any of the 48 approved laboratory tests can differentiate between Zika and the dengue virus

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Pharmacology

Personalized medication

Researchers in the USA have created a custom drug tailored specifically to an american girl with a rare and fatal genetic disorder

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Health

Life-saving vaccines

Butantan produces 100 million doses of nine vaccines each year

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Health

Partnership for a dengue vaccine

Butantan produces 100 million doses of nine different types each year

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Pharmacology

Material releases drug at regular intervals

An international group of researchers has developed a nanostructured material capable of releasing drugs in low concentrations at regular intervals

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Pharmacology

Remedy for menstrual cramps fights schistosomiasis

An anti-inflammatory widely used to alleviate menstrual cramps has been shown through animal testing to be effective at treating schistosomiasis

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Interview

Paola Marcella Camargo Minoprio: A new front against emerging diseases

The Pasteur Institute in Paris, USP, and FIOCRUZ start partnership under coordination of São Paulo biomedical scientist

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Medicine

HIV therapy has prevented 9.5 million deaths

Antiretroviral therapy prevented 9.5 million deaths worldwide between 1995 and 2015, with a global economic benefit of US$1.05 trillion

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PHOTOLAB

Medicinal necklaces

Crnkovic studied microalgae in fresh water as part of her PhD research, which involved bioprospecting for compounds that could help fight cancer

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Entrepreneurship

Healthcare innovation

Award recognizes science projects with potential applications in medicine

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Psychiatry

Battling persistent depression

Studies suggest that low doses of psychedelic anesthetics may be beneficial to people who do not respond to conventional medication

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